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Article

Reconstruct modular phenotype-specific gene networks by knowledge-driven matrix factorization.

Bioinformatics (Oxford, England) - 1 Sept 2009

Yang Xuerui, Zhou Yang, Jin Rong, Chan Christina

Abstract excerpt

MOTIVATION: Reconstructing gene networks from microarray data has provided mechanistic information on cellular processes. A popular structure learning method, Bayesian network inference, has been used to determine network topology despite its shortcomings, i.e. the high-computational cost when analyzing a large number of genes and the inefficiency in exploiting prior knowledge, such as the co-regulation...

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Identifiers

PMID: 19542155
DOI: 10.1093/bioinformatics/btp376
PMCID: PMC2800351

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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