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The endocannabinoid system and pivotal role of the CB <sub>2</sub> receptor in mouse spermatogenesis

18 Jun 2009

Abstract excerpt

The exact role of the endocannabinoid system (ECS) during spermatogenesis has not been clarified. We used purified germ cell fractions representative of all phases of spermatogenesis and primary cultures of spermatogonia. This approach allowed the precise quantification of the cannabinoid receptor ligands, anandamide and 2-arachidonoylglycerol, and of the expression at transcriptional and transductional levels of...

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PMID: 19541620
DOI: 10.1073/pnas.0812789106

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