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Human Sperm Express Cannabinoid Receptor Cb<sub>1</sub>, the Activation of Which Inhibits Motility, Acrosome Reaction, and Mitochondrial Function

1 Feb 2005

Abstract excerpt

Cannabinoids and endocannabinoids negatively influence sperm functions. These substances have been demonstrated in many mammalian tissues, including male and female reproductive tracts, and previous studies have shown the presence of functional receptors for cannabinoids in human sperm. The present study, by means of RT-PCR and Western blot techniques, demonstrates that human sperm express the CB(1), but not...

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PMID: 15562018
DOI: 10.1210/jc.2004-1287

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