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Multiresistance in <i>Pasteurella multocida</i> Is Mediated by Coexistence of Small Plasmids

16 Jun 2009

Abstract excerpt

In most gram-negative bacteria, acquired multiresistance is conferred by large plasmids compiling numerous antimicrobial resistance genes. Here, we show an evolutionary alternative strategy used by Pasteurella multocida to become resistant to multiple clinically relevant antibiotics. Thirteen beta-lactam-resistant clinical isolates, concomitantly resistant to tetracyclines and/or streptomycin as well as to...

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PMID: 19528282
DOI: 10.1128/aac.01522-08

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