Article
Estrogen signaling is not required for prostatic bud patterning or for its disruption by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Toxicology and applied pharmacology - 15 Aug 2009
Allgeier Sarah Hicks, Vezina Chad M, Lin Tien-Min, Moore Robert W, Silverstone Allen E, Mukai Motoko, Gavalchin Jerrie, Cooke Paul S, Peterson Richard E
Abstract excerpt
Estrogens play an important role in prostatic development, health, and disease. While estrogen signaling is essential for normal postnatal prostate development, little is known about its prenatal role in control animals. We tested the hypothesis that estrogen signaling is needed for normal male prostatic bud patterning. Budding patterns were examined by scanning electron microscopy of urogenital sinus epithelium...
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