Article
Candidate therapeutic agents for hepatocellular cancer can be identified from phenotype-associated gene expression signatures.
Cancer - 15 Aug 2009
Braconi Chiara, Meng Fanyin, Swenson Erica, Khrapenko Lyudmyla, Huang Nianyuan, Patel Tushar
Abstract excerpt
BACKGROUND: The presence of vascular invasion in hepatocellular cancer (HCC) correlates with prognosis, and is a critical determinant of both the therapeutic approach and the recurrence or intrahepatic metastases. The authors sought to identify candidate therapeutic agents capable of targeting the invasive phenotype in HCC. METHODS: A gene expression signature associated with vascular invasion derived from 81...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.