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Article

Lessons from BWS twins: complex maternal and paternal hypomethylation and a common source of haematopoietic stem cells.

European journal of human genetics : EJHG - 1 Dec 2009

Bliek Jet, Alders Marielle, Maas Saskia M, Oostra Roelof-Jan, Mackay Deborah M, van der Lip Karin, Callaway Johnatan L, Brooks Alice, van 't Padje Sandra, Westerveld Andries, Leschot Nico J, Mannens Marcel M A M

Abstract excerpt

The Beckwith-Wiedemann syndrome (BWS) is a growth disorder for which an increased frequency of monozygotic (MZ) twinning has been reported. With few exceptions, these twins are discordant for BWS and for females. Here, we describe the molecular and phenotypic analysis of 12 BWS twins and a triplet; seven twins are MZ, monochorionic and diamniotic, three twins are MZ, dichorionic and diamniotic and three twins are...

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Identifiers

PMID: 19513094
DOI: 10.1038/ejhg.2009.77
PMCID: PMC2987023

Genes

DLK1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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