Article
[Diabetes susceptibility genes].
Nihon rinsho. Japanese journal of clinical medicine - 1 Jun 2009
Kasuga Masato
Abstract excerpt
Type 2 diabetes mellitus is a complex polygenic disorder in which common genetics variants interact with environmental factors. Genome-wide association study(GWAS) revealed more than 10 diabetes susceptibility loci for type 2 diabetes mellitus including SNPs in KCNQ1, which was first identified in Japanese by two independent Japanese groups. However, these variants identified by GWAS showed low O.R. (odds ratio)...
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