Article
[The genome and diabetes].
Ugeskrift for laeger - 10 Nov 2014
Allin Kristine Højgaard, Hansen Torben, Pedersen Oluf Borbye
Abstract excerpt
In terms of their genetic architecture monogenic diabetes and type 2 diabetes represent two extremes. Whereas each subtype of monogenic diabetes is caused by one penetrant, rare mutation in a single gene, the genetic susceptibility to type 2 diabetes can be attributed to many low-penetrant variants across the genome. At present, only 10% of the genetic susceptibility to type 2 diabetes can be explained by the...
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