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Article

Computational studies of human galectin-1: role of conserved tryptophan residue in stacking interaction with carbohydrate ligands.

Journal of biomolecular structure & dynamics - 1 Aug 2009

Meynier Christophe, Guerlesquin Francoişe, Roche Philippe

Abstract excerpt

Galectins belong to the family of glycan-binding proteins, defined by at least one conserved carbohydrate-recognition domain with a highly conserved amino acid sequence and affinity for beta galactosides. They all possess a tryptophan residue in the carbohydrate binding site that forms hydrophobic contacts with the carbohydrate ligands. Site directed mutagenesis experiments have shown that this conserved aromatic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19492862
DOI: 10.1080/07391102.2009.10507295

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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