Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic differences in oxidative stress and inflammatory responses to diet-induced obesity do not alter liver fibrosis in mice.

Liver international : official journal of the International Association for the Study of the Liver - 1 Sept 2009

Syn Wing-Kin, Yang Liu, Chiang Dian Jung, Qian Yue, Jung Youngmi, Karaca Gamze, Choi Steve S, Witek Rafal P, Omenetti Alessia, Pereira Thiago A, Diehl Anna Mae

Abstract excerpt

OBJECTIVE: To determine how genetic factors might influence the progression of nonalcoholic fatty liver disease (NAFLD). DESIGN/INTERVENTION: Beginning in adolescence, male C57BL6 (BL6) and 129/SVJ mice were fed control (n=15/group) or high-fat (HF) diets (n=30/group) for 6 months. MAIN OUTCOME MEASURES: Assessed were body weight, insulin resistance, hepatic production of free radicals, expression of cytokines...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Dietary Fats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fatty Liver

Share to Free Radicals

Share to Liver Cirrhosis

Share to Liver Function Tests

Share to Obesity

Share to Oxidative Stress

Source

Open in PubMed Open full text

Identifiers

PMID: 19490416
DOI: 10.1111/j.1478-3231.2009.02036.x
PMCID: PMC3610179

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic differences in oxidative stress and inflammatory responses to diet-induced obesity do not alter liver fibrosis in mice.PMID 19490416Read ↗

Subtle metabolic and liver gene transcriptional changes underlie diet-induced fatty liver susceptibility in insulin-resistant mice.Semantic proximity Read ↗

Mouse models in non‐alcoholic fatty liver disease and steatohepatitis researchSemantic proximity Read ↗

Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF ExpressionSemantic proximity Read ↗

A systematic analysis of rodent models implicates adipogenesis and innate immunity in pathogenesis of fatty liver diseaseSemantic proximity Read ↗

Integrated Ultrasound Characterization of the Diet-Induced Obesity (Dio) Model in Young Adult C57bl/6j Mice: Assessment of Cardiovascular, Renal and Hepatic ChangesSemantic proximity Read ↗

Differences in metabolic and liver pathobiology induced by two dietary mouse models of nonalcoholic fatty liver diseaseSemantic proximity Read ↗

Nutrigenomics of High Fat Diet Induced Obesity in Mice Suggests Relationships between Susceptibility to Fatty Liver Disease and the ProteasomeSemantic proximity Read ↗

A systems biology approach identifies inflammatory abnormalities between mouse strains prior to development of metabolic disease.Semantic proximity Read ↗

A comparative analysis of hepatic pathological phenotypes in C57BL/6J and C57BL/6N mouse strains in non-alcoholic steatohepatitis modelsSemantic proximity Read ↗

Genetic vulnerability to diet-induced obesity in the C57BL/6J mouse: physiological and molecular characteristics.Semantic proximity Read ↗

Divergent compensatory responses to high-fat diet between C57BL6/J and C57BLKS/J inbred mouse strainsSemantic proximity Read ↗

Heterogeneous effects of individual high-fat diet compositions on phenotype, metabolic outcome, and hepatic proteome signature in BL/6 male miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.