Article
CD36 single nucleotide polymorphism is associated with variation in low-density lipoprotein-cholesterol in young Japanese men.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Jun 2009
Morii Toshiyuki, Ohno Yoichi, Kato Norihiro, Hirose Hiroshi, Kawabe Hiroshi, Hirao Keiichi, Eguchi Takashi, Maruyama Tatsuya, Hayashi Matsuhiko, Saito Ikuo, Yazaki Yoshio, Saruta Takao
Abstract excerpt
Macrophages uptake oxidized low-density lipoprotein (LDL) via a scavenger receptor such as CD36 from plasma, and then become foam cells. We examined the association of CD36 gene single nucleotide polymorphisms (SNPs) with certain metabolic characteristics in a young male Japanese population (n = 494). The G allele in a SNP located at +30215 on the 3'-untranslated region (UTR) was significantly correlated with the...
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