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Article

HLA-DR4 as a risk allele for autism acting in mothers of probands possibly during pregnancy.

Archives of pediatrics & adolescent medicine - 1 Jun 2009

Johnson William G, Buyske Steven, Mars Audrey E, Sreenath Madhura, Stenroos Edward S, Williams Tanishia A, Stein Rosanne, Lambert George H

Abstract excerpt

OBJECTIVES: To test whether HLA-DR4 acts in the mother, possibly during pregnancy, to contribute to the phenotype of autistic disorder in her fetus. DESIGN: Transmission disequilibrium testing in case mothers and maternal grandparents. SETTING: Previous studies have consistently shown increased frequency of HLA-DR4 in probands with autism and their mothers, but not their fathers. However, this has been documented...

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Source

Identifiers

PMID: 19487610
DOI: 10.1001/archpediatrics.2009.74

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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