Article
Geographic and temporal trends of transmitted HIV-1 drug resistance among antiretroviral-naïve subjects screening for two clinical trials in North America and Western Europe.
HIV clinical trials - 1 Jan 2000
Rahim Sibtain, Fredrick Linda M, da Silva Barbara A, Bernstein Barry, King Martin S
Abstract excerpt
PURPOSE: To determine the prevalence of transmitted drug resistance (TDR) in antiretroviral (ARV)-naïve HIV-1-infected subjects who were screened for two clinical trials by geographic region and time. METHODS: Studies M03-613 and M05-730 screened ARV-naïve subjects in 2004 and 2005-2006, respectively. Screening drug resistance genotype assays were performed using population sequencing, and prevalence of drug...
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