Article
COPD phenotype description using principal components analysis.
Respiratory research - 29 May 2009
Roy Kay, Smith Jacky, Kolsum Umme, Borrill Zöe, Vestbo Jørgen, Singh Dave
Abstract excerpt
BACKGROUND: Airway inflammation in COPD can be measured using biomarkers such as induced sputum and Fe(NO). This study set out to explore the heterogeneity of COPD using biomarkers of airway and systemic inflammation and pulmonary function by principal components analysis (PCA). SUBJECTS AND METHODS: In 127 COPD patients (mean FEV1 61%), pulmonary function, Fe(NO), plasma CRP and TNF-alpha, sputum differential...
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