Article
Clinical COPD phenotypes: a novel approach using principal component and cluster analyses.
The European respiratory journal - 1 Sept 2010
Burgel P-R, Paillasseur J-L, Caillaud D, Tillie-Leblond I, Chanez P, Escamilla R, Court-Fortune I, Perez T, Carré P, Roche N
Abstract excerpt
Classification of chronic obstructive pulmonary disease (COPD) is usually based on the severity of airflow limitation, which may not reflect phenotypic heterogeneity. Here, we sought to identify COPD phenotypes using multiple clinical variables. COPD subjects recruited in a French multicentre cohort were characterised using a standardised process. Principal component analysis (PCA) was performed using eight...
Topics
- Aged
- Cluster Analysis
- Comorbidity
- Cross-Sectional Studies
- Female
- Humans
- Male
- Middle Aged
- Phenotype
- Principal Component Analysis
- Pulmonary Disease, Chronic Obstructive
