Article
Phenotypic characterization of idiosyncratic drug-induced liver injury: the influence of age and sex.
Hepatology (Baltimore, Md.) - 1 Jun 2009
Lucena M Isabel, Andrade Raúl J, Kaplowitz Neil, García-Cortes Miren, Fernández M Carmen, Romero-Gomez Manuel, Bruguera Miguel, Hallal Hacibe, Robles-Diaz Mercedes, Rodriguez-González Jose F, Navarro Jose Maria, Salmeron Javier, Martinez-Odriozola Pedro, Pérez-Alvarez Ramón, Borraz Yolanda, Hidalgo Ramón
Abstract excerpt
Increased age and female sex are suggested risk factors for drug-induced hepatotoxicity (DILI). We studied the influence of these variables on the propensity to develop DILI, as well as its clinical expression and outcome. All cases of DILI submitted to the Spanish Registry between April 1994 and...
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