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Angiogenesis during primate placentation in health and disease

1 Nov 2003

Abstract excerpt

Normal embryonic development is dependent upon a sufficient oxygen, nutrient and waste exchange through the placenta. In primates including humans, this exchange is attained by successful haemochorial placentation which requires the transformation of maternal intramyometrial spiral arterioles by trophoblast invasion to gain uteroplacental circulation, and establishment and maintenance of a competent fetoplacental...

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PMID: 14611629
DOI: 10.1530/rep.0.1260569

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