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Article

Mutations in the NKX2-5 gene in patients with stroke and patent foramen ovale.

Clinical neurology and neurosurgery - 1 Sept 2009

Belvís Robert, Tizzano Eduardo F, Martí-Fàbregas Joan, Leta Rubén G, Baena Manel, Carreras Francesc, Pons-Lladó Guillem, Baiget Montserrat, Martí-Vilalta Josep Lluis

Abstract excerpt

OBJECTIVE: Patent foramen ovale (PFO) has been related to stroke but its existence has not been explained to date. NKX2-5 is the most implicated gene in fetal atrial septation. We studied NKX2-5 with respect to the presence or absence of PFO in stroke patients. METHODS: A prospective analysis of NKX2-5 regarding age, gender, PFO, right-to-left shunt (RLS) size and atrial septal aneurysm (ASA) was performed in...

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PMID: 19464101
DOI: 10.1016/j.clineuro.2009.04.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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