Article
Susceptibility of antiviral drugs against 2009 influenza A (H1N1) virus.
Biochemical and biophysical research communications - 31 Jul 2009
Rungrotmongkol Thanyada, Intharathep Pathumwadee, Malaisree Maturos, Nunthaboot Nadtanet, Kaiyawet Nopphorn, Sompornpisut Pornthep, Payungporn Sanchai, Poovorawan Yong, Hannongbua Supot
Abstract excerpt
The recent outbreak of the novel strain of influenza A (H1N1) virus has raised a global concern of the future risk of a pandemic. To understand at the molecular level how this new H1N1 virus can be inhibited by the current anti-influenza drugs and which of these drugs it is likely to already be resistant to, homology modeling and MD simulations have been applied on the H1N1 neuraminidase complexed with...
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