Article
Metal ions binding to recA inteins from Mycobacterium tuberculosis.
Molecular bioSystems - 1 Jun 2009
Zhang Liyun, Zheng Yuchuan, Xi Zhaoyong, Luo Zhaofeng, Xu Xiaolong, Wang Chunyu, Liu Yangzhong
Abstract excerpt
Zinc has been found in the crystal structures of inteins and the zinc ion can inhibit intein splicing both in vitro and in vivo. The interactions between metal ions and three minimized recA inteins have been studied in this work. Isothermal titration calorimetry (ITC) results show that the zinc binding affinity to three inteins is in the order of DeltaI-SM > DeltaDeltaI(hh)-SM approximately DeltaDeltaI(hh)-CM,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.