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Article

Genome-wide association study identifies single-nucleotide polymorphism in KCNB1 associated with left ventricular mass in humans: the HyperGEN Study.

BMC medical genetics - 19 May 2009

Arnett Donna K, Li Na, Tang Weihong, Rao Dabeeru C, Devereux Richard B, Claas Steven A, Kraemer Rachel, Broeckel Ulrich

Abstract excerpt

BACKGROUND: We conducted a genome-wide association study (GWAS) and validation study for left ventricular (LV) mass in the Family Blood Pressure Program-HyperGEN population. LV mass is a sensitive predictor of cardiovascular mortality and morbidity in all genders, races, and ages. Polymorphisms of candidate genes in diverse pathways have been associated with LV mass. However, subsequent studies have often failed...

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Source

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Identifiers

PMID: 19454037
DOI: 10.1186/1471-2350-10-43
PMCID: PMC2692849

Genes

KCNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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