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Glyoxalase I Glu111Ala polymorphism in patients with breast cancer.

Cancer investigation - 1 Jul 2009

Germanová Alexandra, Germanová Anna, Tesarová Petra, Jáchymová Marie, Zvára Karel, Zima Tomás, Kalousová Marta

Abstract excerpt

Effect of advanced glycation end products (AGEs) in the pathogenesis of cancer could be diminished by interaction with soluble RAGE or by reducing AGE-precursors via glyoxalase I. Glu111Ala polymorphism of glyoxalase I gene, AGEs, and sRAGE serum levels were studied in 113 breast cancer patients and in 58 controls. Higher frequency of the mutated C allele was found in patients with negative estrogen receptors and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19452310
DOI: 10.1080/07357900802350822

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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