Article
Polymorphisms in PDCD1 gene are not associated with Wegener's granulomatosis.
Rheumatology international - 1 Aug 2009
Sakthivel Priya, Giscombe Ricardo, Ramanujam Ryan, Lefvert Ann Kari
Abstract excerpt
Genetic association of programmed cell death-1 (PDCD1) has been implicated in several autoimmune inflammatory disorders. Hence, in this study, our main objective is to evaluate the association of PDCD1 gene to Wegener's granulomatosis (WG). We, thus, analyzed three single nucleotide polymorphisms (SNPs) in PDCD1 gene among WG patients and controls. Further, we quantified circulating serum levels of soluble (s)...
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