Article
The effects of obesity and HER-2 polymorphisms as risk factors for endometrial cancer in Korean women.
BJOG : an international journal of obstetrics and gynaecology - 1 Jul 2009
Tong S-Y, Ha S-Y, Ki K-D, Lee J-M, Lee S-K, Lee K-B, Kim M-K, Cho C-H, Kwon S-Y
Abstract excerpt
OBJECTIVE: To evaluate the relationship between single nucleotide polymorphisms (SNPs) in the HER-2 gene, body mass index (BMI) and the risk of endometrial cancer. DESIGN: Case-control study. SETTING: Medical centres in Korea. SAMPLE: DNA samples and medical histories were obtained from 125 endometrial cancer cases and 302 controls. METHODS: The genotypes evaluated in HER-2 at positions -423, -655, -776, -857,...
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