Article
Epidermal growth factor receptor and human epidermal growth factor receptor 2 gene polymorphisms in endometrial cancer in a Japanese population.
Reproductive sciences (Thousand Oaks, Calif.) - 1 May 2007
Kitao Keisuke, Yoshida Shigeki, Kennedy Stephen, Takemura Naoya, Sugimoto Makoto, Deguchi Masashi, Ohara Noriyuki, Maruo Takeshi
Abstract excerpt
Endometrial cancer is associated with both EGFR and HER2 receptor activation. The EGFR and HER2 genes could be disease susceptibility candidate genes for this cancer. This study was conducted to investigate a possible association between EGFR and HER2 gene polymorphisms and endometrial cancer and the influence of these polymorphisms on the clinical outcome of endometrial cancer patients in a Japanese population....
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