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Article

Osteogenic differentiation of mesenchymal stem cells promoted by overexpression of connective tissue growth factor

1 May 2009

Abstract excerpt

OBJECTIVE: Large segmental bone defect repair remains a clinical and scientific challenge with increasing interest focusing on combining gene transfection with tissue engineering techniques. The aim of this study is to investigate the effect of connective tissue growth factor (CTGF) on the proliferation and osteogenic differentiation of the bone marrow mesenchymal stem cells (MSCs). METHODS: A CTGF-expressing...

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PMID: 19434762
DOI: 10.1631/jzus.b0820252

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