Article
Bordetella bronchiseptica aroA mutant as a live vaccine vehicle for heterologous porcine circovirus type 2 major capsid protein expression.
Veterinary microbiology - 18 Sept 2009
Kim Taejung, Toan Nguyen Tat, Seo Jayoung, Jung Bockgie, Lee Jaeil, Lee Bongjoo
Abstract excerpt
Porcine circovirus type 2 (PCV2) infections cause important respiratory diseases in the pig industry and are associated with many bacterial, mycoplasmal, and viral complications. In this study, a heterologous PCV2 major capsid protein (MCP) was expressed in the Bordetella bronchiseptica aroA mutant strain (BBS-MCP) and used as a live vaccine vehicle. Mice and pigs were immunized with live BBS-MCP via the...
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