Article
Identification of a pleiotropic locus on chromosome 7q for a composite left ventricular wall thickness factor and body mass index: the HyperGEN Study.
BMC medical genetics - 9 May 2009
Tang Weihong, Devereux Richard B, Li Na, Oberman Albert, Kitzman Dalane W, Rao Dabeeru C, Hopkins Paul N, Claas Steven A, Arnett Donna K
Abstract excerpt
BACKGROUND: Left ventricular (LV) mass and wall thickness are closely associated with measures of body size and blood pressure and also correlated with systolic and diastolic function, suggesting a contribution of common physiologic mechanisms, including pleiotropic genes, to their covariation. METHODS: Doppler echocardiography was performed in 434 African-American (1344 individuals) and 284 white families (1119...
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