Article
Emergence of complex haplotypes from microevolutionary variation in sequence and structure of Colias phosphoglucose isomerase.
Journal of molecular evolution - 1 May 2009
Wang Baiqing, Watt Ward B, Aakre Christopher, Hawthorne Noah
Abstract excerpt
A molecular evolutionary explanation of natural genetic variation requires analysis of specific variants' evolutionary dynamics. To pursue this for phosphoglucose isomerase (PGI) of Colias butterflies, whose polymorphism is maintained by strong natural selection, we assembled a large data set of wild haplotypes, highly variable at the amino acid and DNA levels. The most common electrophoretic, i.e., charge...
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