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Article

From DNA to fitness differences: sequences and structures of adaptive variants of Colias phosphoglucose isomerase (PGI).

Molecular biology and evolution - 1 Mar 2006

Wheat Christopher W, Watt Ward B, Pollock David D, Schulte Patricia M

Abstract excerpt

Colias eurytheme butterflies display extensive allozyme polymorphism in the enzyme phosphoglucose isomerase (PGI). Earlier studies on biochemical and fitness effects of these genotypes found evidence of strong natural selection maintaining this polymorphism in the wild. Here we analyze the molecular features of this polymorphism by sequencing multiple alleles and modeling their structures. PGI is a dimer with...

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Identifiers

PMID: 16292000
DOI: 10.1093/molbev/msj062
PMCID: PMC2943955

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Source receipt: pubmed, retrieved 7 Sept 2026.

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