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Simulated microgravity decreases DNA repair capacity and induces DNA damage in human lymphocytes

4 May 2009

Abstract excerpt

The effect of simulated microgravity on DNA damage and apoptosis is still controversial. The objective of this study was to test whether simulated microgravity conditions affect the expression of genes for DNA repair and apoptosis. To achieve this objective, human lymphocyte cells were grown in a NASA-developed rotating wall vessel (RWV) bioreactor that simulates microgravity. The same cell line was grown in...

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PMID: 19415677
DOI: 10.1002/jcb.22171

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