Article
Nonmetric multidimensional scaling corrects for population structure in association mapping with different sample types.
Genetics - 1 Jul 2009
Zhu Chengsong, Yu Jianming
Abstract excerpt
Recent research has developed various promising methods to control for population structure in genomewide association mapping of complex traits, but systematic examination of how well these methods perform under different genetic scenarios is still lacking. Appropriate methods for controlling genetic relationships among individuals need to balance the concern of false positives and statistical power, which can...
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