Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cellular and molecular origin of circumpapillary dysgenesis of the pigment epithelium.

Ophthalmology - 1 May 2009

Tosi Joaquin, Janisch Kerstin M, Wang Nan-Kai, Kasanuki J Mie, Flynn John T, Lin Chyuan-Sheng, Tsang Stephen H

Abstract excerpt

PURPOSE: We studied clinical phenotyping and TEAD1 expression in mice and humans to gain a better understanding of the primary origin in the pathogenesis of circumpapillary dysgenesis of the pigment epithelium. DESIGN: Observational case series and experimental study. PARTICIPANTS: Three female patients from an affected family were included for phenotypic study. Mice and human tissues were used for biochemistry...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Choroid Diseases
Share to Eye Abnormalities

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluorescent Antibody Technique, Indirect

Share to Hepatocyte Nuclear Factor 3-beta

Share to Retinal Degeneration

Share to Retinal Pigment Epithelium

Share to Tomography, Optical Coherence

Share to YAP-Signaling Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 19410955
DOI: 10.1016/j.ophtha.2008.10.032
PMCID: PMC2717946

Genes

TEAD1
RPE
FOXA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Cellular and molecular origin of circumpapillary dysgenesis of the pigment epithelium.PMID 19410955Read ↗

3D iPSC modeling of the retinal pigment epithelium-choriocapillaris complex identifies factors involved in the pathology of macular degenerationSemantic proximity Read ↗

Epithelial–mesenchymal transition of the retinal pigment epithelium causes choriocapillaris atrophySemantic proximity Read ↗

Epigenetic regulation of retinal development and diseaseSemantic proximity Read ↗

The <i>Dct</i> <sup>-/-</sup> mouse model to unravel retinogenesis misregulation in patients with albinismSemantic proximity Read ↗

Iris phenotypes and pigment dispersion caused by genes influencing pigmentation.Semantic proximity Read ↗

Characterization of new transcripts enriched in the mouse retina and identification of candidate retinal disease genes.Semantic proximity Read ↗

Recent advances in the molecular biology of pigmentation: mouse models.Semantic proximity Read ↗

Conditional knockdown of DNA methyltransferase 1 reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesisSemantic proximity Read ↗

Generating iPSC-Derived Choroidal Endothelial Cells to Study Age-Related Macular DegenerationSemantic proximity Read ↗

DAPL1, a susceptibility locus for age-related macular degeneration, acts as a novel suppressor of cell proliferation in the retinal pigment epitheliumSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.