Article
Decreased muscle ACE activity enhances functional response to endurance training in rats, without change in muscle oxidative capacity or contractile phenotype.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Jul 2009
Habouzit Estelle, Richard Hélène, Sanchez Hervé, Koulmann Nathalie, Serrurier Bernard, Monnet Rachel, Ventura-Clapier Renée, Bigard Xavier
Abstract excerpt
In the present study, we tested the hypothesis that chronic ANG I-converting enzyme (ACE) inhibition could improve the training-induced improvement in endurance exercise performance and that this could be related to enhanced skeletal muscle metabolic efficiency. Female Wistar rats were assigned to four groups comprising animals either maintained sedentary or endurance trained (Sed and Tr, respectively), and...
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