Article
Blood chimerism confounds genetic relative susceptibility testing for classical scrapie in sheep.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc - 1 May 2009
Schneider David A, Tibary Ahmed, Raudsepp Terje, Das Pranab J, O'Rourke Katherine I
Abstract excerpt
Classical scrapie disease is a transmissible spongiform encephalopathy of sheep that is enzootic in the United States. Susceptibility of sheep to classical scrapie is linked to single nucleotide polymorphisms in the prion protein gene (PRNP), forming the basis for genetic testing strategies used by national efforts to eradicate scrapie. Such efforts are occasionally hampered by inconclusive results stemming from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.