Article
Cytokine gene polymorphisms associated with rheumatoid arthritis and periodontitis in Japanese adults.
Journal of periodontology - 1 May 2009
Kobayashi Tetsuo, Murasawa Akira, Ito Satoshi, Yamamoto Kouji, Komatsu Yasutaka, Abe Asami, Sumida Takayuki, Yoshie Hiromasa
Abstract excerpt
BACKGROUND: Cytokines play a major role in the pathogenesis of rheumatoid arthritis (RA) and periodontitis. Both diseases were previously shown to be partly influenced by cytokine gene polymorphisms. Therefore, we evaluated whether the distributions of the cytokine genotypes were unique to subjects with both diseases. METHODS: The study subjects consisted of Japanese adults with RA (RA group; n = 153),...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Arthritis, Rheumatoid
- Asian People
- Case-Control Studies
- Cytokines
- Female
- Gene Frequency
- Humans