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MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival

18 May 2011

Abstract excerpt

BACKGROUND: MicroRNAs are small RNA species that regulate gene expression post-transcriptionally and are aberrantly expressed in many cancers including hematological malignancies. However, the role of microRNAs in the pathogenesis of multiple myeloma (MM) is only poorly understood. We therefore used microarray analysis to elucidate the complete miRNome (miRBase version 13.0) of purified tumor (CD138+) cells from...

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PMID: 21592325
DOI: 10.1186/1745-6150-6-23

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