Article
Heritability of Trail Making Test performance in multiplex schizophrenia families: implications for the search for an endophenotype.
European archives of psychiatry and clinical neuroscience - 1 Dec 2009
Quiñones Raúl Mendoza, Calderín Yuranny Cabral, Domínguez Mayelin, Bravo Tania M, Berazaín Adnelys Reyes, García Alexander, Caballero Antonio, Reyes Migdyrai Martín
Abstract excerpt
The impairment of the Trail Making Test (TMT) performance as a measure of executive function deficits has been found both in patients with schizophrenia and in their unaffected first-degree relatives, suggesting that it might be considered as a familial vulnerability marker, but its heritability estimates are not well known. This study investigated the genetic heritability of impairments in TMT performance using...
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