Article
Alcohol dehydrogenase controls the flux from ethanol into lipids in Drosophila larvae. A 13C NMR study.
The Journal of biological chemistry - 15 Nov 1991
Freriksen A, Seykens D, Scharloo W, Heinstra P W
Abstract excerpt
The dependence of the flux in the alcohol-degrading pathway on the activity of alcohol dehydrogenase was investigated in Drosophila larvae. Third-instar larvae were supplied with [2-13C]ethanol as a dietary carbon source. Specific carbon enrichments in de novo synthesized fatty acids were determined in vitro by means of 13C nuclear magnetic resonance spectroscopy. Carbon fluxes deduced from these enrichment...
Topics
- Alcohol Dehydrogenase
- Animals
- Carbon Isotopes
- Drosophila
- Ethanol
- Genotype
- Isoenzymes
- Kinetics
- Larva
- Lipid Metabolism
- Magnetic Resonance Spectroscopy