Article
Paternal allele of IGF2 gene haplotype CTG is associated with fetal and placental growth in Japanese.
Pediatric research - 1 Aug 2009
Nagaya Ken, Makita Yoshio, Taketazu Genya, Okamoto Toshio, Nakamura Eiki, Hayashi Tokitsugi, Fujieda Kenji
Abstract excerpt
IGF-II associates with feto-placental growth in rodent and human. We determined three tag-single nucleotide polymorphisms (SNPs) to investigate haplotype frequency of IGF2 relative to size at birth in 134 healthy Japanese infants. In addition, a total of 276 healthy infants were investigated to determine whether common genetic variation of IGF2 might contribute to feto-placental growth using haplotype analysis....
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