Article
Hedgehog does not guide migrating Drosophila germ cells.
Developmental biology - 15 Apr 2009
Renault Andrew D, Ricardo Sara, Kunwar Prabhat S, Santos Ana, Starz-Gaiano Michelle, Stein Jennifer A, Lehmann Ruth
Abstract excerpt
In many species, the germ cells, precursors of sperm and egg, migrate during embryogenesis. The signals that regulate this migration are thus essential for fertility. In flies, lipid signals have been shown to affect germ cell guidance. In particular, the synthesis of geranylgeranyl pyrophosphate through the 3-hydroxy-3-methyl-glutaryl coenzyme A reductase (Hmgcr) pathway is critical for attracting germ cells to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
