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Article

Inhibiting complement activation on cells at the step of C3 cleavage.

Vaccine - 30 Dec 2008

Liszewski M Kathryn, Fang Celia J, Atkinson John P

Abstract excerpt

Nearly half of the proteins in the complement system serve in regulation. Control at the central step of C3 activation is provided by an orchestrated interplay of membrane and plasma regulators. A model system employing Chinese hamster ovary (CHO) cells transfected with human regulators was employed to assist in making functional comparisons. Also, in this experimental setup, the pathway and magnitude of...

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Identifiers

PMID: 19388160
DOI: 10.1016/j.vaccine.2008.11.001
PMCID: PMC2768381

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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