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Article

High diversity of Mycobacterium tuberculosis genotypes in South Africa and preponderance of mixed infections among ST53 isolates.

Journal of clinical microbiology - 1 Jun 2009

Stavrum Ruth, Mphahlele Matsie, Ovreås Kristi, Muthivhi Tshilidzi, Fourie P Bernard, Weyer Karin, Grewal Harleen M S

Abstract excerpt

The reemergence of tuberculosis (TB) has become a major health problem worldwide, especially in Asia and Africa. Failure to combat this disease due to nonadherence or inappropriate drug regimens has selected for the emergence of multiple-drug-resistant (MDR) TB. The development of new molecular genotyping techniques has revealed the presence of mixed Mycobacterium tuberculosis infections, which may accelerate the...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Antitubercular Agents
Bacterial Typing Techniques
Cluster Analysis
DNA Fingerprinting
DNA, Bacterial
Drug Resistance, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Female

Genotype

Humans

Interspersed Repetitive Sequences

Male

Middle Aged

Minisatellite Repeats

Mycobacterium tuberculosis

Source

Open in PubMed Open full text

Identifiers

PMID: 19386854
DOI: 10.1128/JCM.02167-08
PMCID: PMC2691085

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-19386854-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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