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Article

High diversity of Mycobacterium tuberculosis genotypes in South Africa and preponderance of mixed infections among ST53 isolates.

Journal of clinical microbiology - 1 Jun 2009

Stavrum Ruth, Mphahlele Matsie, Ovreås Kristi, Muthivhi Tshilidzi, Fourie P Bernard, Weyer Karin, Grewal Harleen M S

Abstract excerpt

The reemergence of tuberculosis (TB) has become a major health problem worldwide, especially in Asia and Africa. Failure to combat this disease due to nonadherence or inappropriate drug regimens has selected for the emergence of multiple-drug-resistant (MDR) TB. The development of new molecular genotyping techniques has revealed the presence of mixed Mycobacterium tuberculosis infections, which may accelerate the...

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Identifiers

PMID: 19386854
DOI: 10.1128/JCM.02167-08
PMCID: PMC2691085

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