Article
Discovering genetic polymorphisms in next-generation sequencing data.
Plant biotechnology journal - 1 May 2009
Imelfort Michael, Duran Chris, Batley Jacqueline, Edwards David
Abstract excerpt
The ongoing revolution in DNA sequencing technology now enables the reading of thousands of millions of nucleotide bases in a single instrument run. However, this data quantity is often compromised by poor confidence in the read quality. The identification of genetic polymorphisms from this data is therefore problematic and, combined with the vast quantity of data, poses a major bioinformatics challenge. However,...
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