Article
Radiation sensitivity of human B-lineage lymphoid precursor cells.
International journal of radiation oncology, biology, physics - 1 Nov 1991
Uckun F M, Mitchell J B, Obuz V, Park C H, Waddick K, Friedman N, Oubaha L, Min W S, Song C W
Abstract excerpt
We studied the radiation sensitivity of eight immunophenotypically distinct B-lineage lymphoid precursor cell (LPC) lines of acute lymphoblastic leukemia (ALL) or fetal liver origin corresponding to discrete developmental stages of human B-cell ontogeny. The radiation sensitivity of B-lineage LPC showed a temporal association with the distinct stages of development. FL112 and FL114 fetal liver pro-B cells (Stage...
Topics
- B-Lymphocytes
- Cell Survival
- Genotype
- Humans
- Immunophenotyping
- Neoplasm Staging
- Precursor Cell Lymphoblastic Leukemia-Lymphoma
- Radiation Tolerance
- Tumor Cells, Cultured
