Article
Predicted phenotypes of dry eye: proposed consequences of its natural history.
The ocular surface - 1 Apr 2009
Bron Anthony J, Yokoi Norihiko, Gafney Eamonn, Tiffany John M
Abstract excerpt
This paper reviews current knowledge of the pathophysiology of dry eye and predicts that the clinical picture in late disease differs in both severity and quality from that in early disease. It is hypothesized that hybrid forms evolve, in which aqueous-deficient dry eye (ADDE) takes on features of evaporative dry eye (EDE) and vice versa. As a consequence, early and late forms may require different diagnostic...
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