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Article

Exogenous transforming growth factor beta1 replacement and fertility in male Tgfb1 null mutant mice.

Reproduction, fertility, and development - 1 Jan 2009

McGrath Leanne J, Ingman Wendy V, Robker Rebecca L, Robertson Sarah A

Abstract excerpt

Analysis of Tgfb1 null mutant mice has demonstrated that the cytokine transforming growth factor beta1 (TGFB1) has essential non-redundant roles in fertility. The present study attempted to alleviate the infertility phenotype of Tgfb1 null mutant male mice by administration of exogenous TGFB1, either orally by colostrum feeding or subcutaneously by delivery of recombinant human latent TGFB1 (rhLTGFB1) via osmotic...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19383262
DOI: 10.1071/RD08294

Genes

TGFB1
TGFB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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