Article
Reactive nitrogen intermediate susceptibility of Mycobacterium tuberculosis genotypes in an urban setting.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 May 2009
Inumaru V T G, Nogueira P A, Butuem I V, Riley L W, Ferrazoli L
Abstract excerpt
BACKGROUND: Mycobacterium tuberculosis genotypes resistant to reactive nitrogen intermediates (RNI) predominate in certain urban communities, suggesting that this phenotype influences disease transmission. OBJECTIVE: To compare different M. tuberculosis genotypes for resistance to RNI generated in vitro. DESIGN: We genotyped 420 M. tuberculosis isolates from a neighborhood in Sao Paulo, Brazil, and analyzed them...
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