Article
Association of homozygous SDF-1 3'A genotype with proliferative diabetic retinopathy.
Acta diabetologica - 1 Mar 2010
Djuric Zdenka, Sharei Vahid, Rudofsky Gottfried, Morcos Michael, Li Huiqing, Hammes Hans-Peter, Nawroth Peter P, Bierhaus Angelika, Humpert Per M, Jonas Jost B
Abstract excerpt
Stromal cell-derived factor 1 (SDF-1) is involved in the development of experimental proliferative retinopathy. Since little data are available on the genetic predisposition or on biomarkers predicting the development of proliferative retinopathy, we assessed the distribution of the SDF-1 3'A genotype in 130 diabetic patients with retinopathy. In patients with proliferative retinopathy, the frequency of the...
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